CAGE Bio is a biotech company using ionic liquid technology for skin penetration, keeping drug concentration in blood plasma minimal and helping to improve safety. Our topical programs for moderate to severe skin diseases span atopic dermatitis, vitiligo and alopecia areata, with DNA aptamer and siRNA candidates.

An ionic liquid (IL) is a liquid salt in which the ions are poorly coordinated by association only with ionic bonds and no covalent bonds. As a result, these solvents remain liquid at or below room temperature and have excellent solvation properties with very low vapor pressure.
Ionic Liquid Platform uses structural heterogeneity of cations & anions to enhance membrane permeation.

Delivers wide range of drug APIs including small molecules, peptides, proteins and nucleic acids across the stratum corneum following topical administration, with minimal impact on barrier function.

Enables choice of cations and anions to engineer diverse ILs with
tailor‐made properties for multiple therapeutic areas.

Extensive anti-microbial properties.

CAGE Bio has accumulated a vast amount of in vitro and in vivo evidence supporting the role of ionic liquids in improving tissue-specific delivery of therapeutic entities into the skin.
