CAGE Bio is revolutionizing the treatment of chronic skin conditions with its groundbreaking Ionic Liquid platform. Our advanced immuno-dermatology therapies deliver potent drugs topically achieving high effect-site bioavailability for high efficacy with low systemic bioavailability for minimizing systemic side effects
Nitin has been actively engaged in pharmaceutical product development in
the industry since Feb 1998, when (at Elan Pharmaceuticals), he first started studying interactions between powders and polymer surfaces to improve the efficiencies of pulmonary dry powder inhalation products for asthma and COPD. He moved into formulation and process development thereafter and became fully entrenched in pharmaceutical dosage form development. He has actively contributed to various drug delivery products from new chemical entities to drug delivery applications for known molecules. In 2006, he started working on a transdermal product for post- operative pain at ALZA Corporation. He led the development of the next-generation version of IONSYS, a drug-device combination transdermal product. He believed in the technology and the value of the product, so when the company terminated the program, he joined with outside investors and co-created Incline Therapeutics to get this product approved and to the market.
Prof. Mitragotri is a global leader in drug delivery. His research has advanced fundamental understanding of biological barriers and has led to the development of new technologies for treating various indications in dermatology, oncology, metabolic disorders, neurology and infectious diseases. Many of his technologies have advanced to human clinical studies and products. Currently, he is employed as the Hiller Professor of Bioengineering and Hansjorg Wyss Professor of Biologically Inspired Engineering at Harvard John A. Paulson School of Engineering and Applied Sciences. He is an elected member of the NAE and NAM, and an elected fellow of NAI, AAAS, CRS, BMES, AIMBE, and AAPS.
Jeff is a veteran of the pharmaceutical industry with 40 years of
leadership experience in developing and commercializing new
medical therapies. He has invented products leading to
significant improvements in patient care and has numerous
patents issued by the USPTO in healthcare. He has a track
record of success in developing new companies from start-up,
through IPO and M&A exits. He was the co-founder and COO at
ZS Pharma, acquired by Astra Zeneca in 2015 for $2.7 billion.
He is the inventor of the Mucinex product line for Adams
Respiratory Therapeutics. He developed and executed the R&D
and Regulatory strategy as VP of Development and Regulatory
Affairs, which subsequently was acquired by Reckitt Benckiser
for $2.3 billion in 2007. Jeff held senior positions at Encysive
Pharmaceuticals, Medeva Americas, Marion Merrell Dow and
Abbott Laboratories. Jeff is currently serving as the President
and CEO of Renibus Therapeutics which he co-founded.
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CAGE Bio Announces Phase 2b Trial for CGB-500 (1% Tofacitinib), a Breakthrough Topical JAK Inhibitor for Moderate to Severe Atopic Dermatitis